RegPep2016, register now for attractive fees !
Posted the 2015/10/07
On behalf of the International Regulatory Peptide Society, the Summer Neuropeptide Conferences, the European Neuropeptide Club and the Groupe Français des Peptides et des Protéines, we would like to invite you to participate to RegPep2016 that will be held in Rouen (Normandy, France) from July 12th to 14th, 2016. The venue of RegPep2016 will be the Law Faculty, a beautiful new building located in downtown Rouen, on the bank of the Seine River, within walking distance from the Place du Vieux-Marché (where Joan of Arc was burnt alive in 1431) and the famous Cathedral, painted by Claude Monet.

The scientific program will comprise a Lay-public Lecture, 3 Plenary Lectures, 20 Symposia with 80 State-of-the-Art Lectures, 32 free oral communications selected from the abstracts, 12 communications from young investigators and 2 poster sessions.

Sessions will address both basic and clinical issues. Participation of clinicians and private companies is encouraged. Basic research will also be well represented with some sessions addressing for instance evolutionary aspects. Attending RegPep2016, you will be able to learn about the most recent advances on peptides that regulate cell, tissue or organ functions in physiological or pathological conditions. For more information regarding the program, please visit the RegPep2016 website (

Besides the scientific program, the social events, included in the registration fee of all participants and accompanying persons, will comprise a get-together party on Tuesday July 12th, a visit of Rouen Impressionist Museum and a Banquet Dinner on Wednesday July 13th, and a visit of Rouen plus a firework display on the Seine River on Thursday July 14th. Travel awards for young investigators (graduate students and postdoctoral fellows) will be available. Satellite meetings will be organized before the RegPep2016 (July 11th) and an optional excursion to Etretat Alabaster coast will be proposed after the meeting (July 15th). We very much hope that you will be able to join us for this major international meeting on bioactive peptides in Rouen in 2016. During this meeting, you will meet old friends and colleagues, and initiate new relationships with others working in fields similar to your own.


Registrations are now open on the website with an attractive fee until January 31th, 2016 for early registration. If there is anything that we can do to help you attend the congress, please do not hesitate to contact us directly at

Registration to RegPep2016
Posted the 2015/09/16

Registration to the RegPep2016 are now open. A very attractive price is available until January 31, 2016. More information regarding the meeting and the scientific program available on our website :

visit to BREST
Posted the 2015/04/07
February 2th 2015. Two PhD students of the UMR-I 02 INERIS-URCA-ULH Stress Environnementaux et BIOsurveillance des milieux aquatiques (University of Le Havre) have visited the Laboratory of Neurophysiology (University of Brest).
New Publication
Posted the 2015/04/07
align="center">Divergent cardio-ventilatory and locomotor effects of centrally and peripherally administered urotensin II and urotensin II-related peptides in the unanesthethized trout

Gilmer Vanegas1, Jérôme Leprince2, Frédéric Lancien1, Nagi Mimassi1, Hubert Vaudry2, Jean-Claude Le Mével1*


1INSERM UMR1101, Laboratoire de Neurophysiologie, SFR ScInBioS, Université de Brest, France

2INSERM U982, UA CNRS, Différenciation et Communication Neuronale et Neuroendocrine, Université de Rouen, Mont-Saint-Aignan, France.

accepted for publication in Frontiers in Neurosciences, section Neuroendocrine Science (2015).



Recruitment & Happy new year
Posted the 2015/01/20
Mrs Julia LE GALLO has been recruited on the PeReNE project to participate with Mrs Marine LE MERCIER to the PeReNE project closure.


Mrs Lisa VIENNA was recruited as a trainee in charge of communication for the PeReNE project. Its mission focuses on the production of a document on the scientific results obtained thanks to PeReNE project.

Mrs VIENNA also carried the project’s greeting card 2015 you will find below.

Posted the 2015/01/14

On January 20, 2015 at 1:30 PM, Dr Xavier XIFRO from Gerone Univerity (Spain), will give a conference entitled « Characterization of the role of PACAP in Huntington's disease » in the PRIMACEN meeting room, room 308, of the main building of the Science Faculty, campus of Mont-Saint Aignan, University of Rouen (Mont-Saint-Aignan, France).

program PeReNE fianl meeting
Posted the 2014/12/24
January 15th, 2015

9 h 45: Registration + Coffee

10 h – 12 h 30: Steering committee

12 h 30 – 14 h: Lunch

14 h – 14 h 25: Oral communication 1 - Alexandrine Robert: Neuroendocrine disruption in the shore crab Carcinus maenas: effects of fluoxetine on neuropetides of the CHH-family, glycaemia and ecdysteroid levels

14 h 25 – 14 h 50: Oral communication 2 - Alex Ford: Parasitic and pharmacological neuromodulation of wildlife behaviour

14 h 50 – 15 h 15: Oral communication 3 - Maria Roth De Carvallo: Pituitary Adenylate-Cyclase Activating Polypetide (PACAP) modulates microglial cells phenotype through C/EBP-β pathway and regulation of specific microRNAs

15 h 15 – 17 h 00: Posters + Coffee break

17 h 00 – 17 h 40 h: Conference 1 - Heinrich Dircksen: Bioactive peptide in arthropods

19 h 30 – 22 h: Dinner


January 16th, 2015

9 h – 9 h 40: Conference 2 - Nathalie Thiriet: Protective and Proliferative Functions of NPY within the Brain

9 h 40 – 10 h 05: Oral communication 3 - Rhita Lamtahri: Paradoxical effect of the neuroprotective peptide ODN in cerebral ischemia

10 h 05 – 10 h 55: Posters + Coffee break

10 h 55 – 11h 35: Conference 4 - Angelita Rebollo: Enhanced serum proteolysis resitance of cell penetrating peptides

11 h 35 – 12 h 00: Oral communication 5 - Pierre Michaël Coly: GPCR-Induced chemotactic migration requires mitigation of autophagy: involvement in glial cell invasion

12 h 00 – 13 h 30: Lunch

13 h 30 – 14 h 20: Oral communication 6 - Carla Delépée: Cyclic peptide hormones: conformation, dynamics and pharmacophores of urotensin and vasopressin

14 h 20 – 14 h 45: Coffee break

14 h 45 – 15 h: Prices and closure

Meeting in Brest
Posted the 2014/12/24
In October 2014 Prof. Darek GORECKI and Dr. Eugen BARBU visited the Neurophysiology Laboratory at the Faculty of Medicine, University of Brest, where they had meetings with Prof. Jean-Claude LE MEVEL’s research group; on this occasion Dr. BARBU gave a talk on the topic ofpolymeric nanoparticles for drug delivery.


PeReNE Final Meeting
Posted the 2014/12/15
v>A message to let you know that upon request, we have modified the dead line for registration and abstract submission to the PeReNE Final Meeting. The new dead line is now Wednesday 17th evening. Be aware that because of the Christmas vacation, we won't be able to extend any further.Thank you for your comprehension. 

Most oral presentation will be 20 minutes plus 5 minutes question.</
Conference of Dr Jerome Leprince
Posted the 2014/11/04
Development of a new class of neuropeptides analogues that modulate food intake.

Caen, on the 5 november 2014, 6th scientific journey of faculty of pharmacy, UFR de Pharmacie, Boulevard Becquerel, amphi 8.

Fourth PeReNE Steering Committee
Posted the 2014/10/21
Science Faculty, 33 rue Saint Leu, Amiens



Monday October 27th

12h00: Welcome in the hall of the science faculty.

12h30: Lunch for every participant in the university area.

14h00: Steering committee and exchange between partners.

19h30: Dinner at the “Brasserie Jules”.


Tuesday October 28th

9h00: Welcome and conference launch

David Vaudry, Nicolas Harmer, Olivier Lesouhaitier, Paul Gard, Moïse Coeffier, Thomas Knigge

12h00: Lunch for every participant in the university area.

14h00: Visits of two structures dedicated to protein analysis.

-          Academic platforms: RLC de Rootlines Technology and the analytical platform CRRBM (Regional Center for Resources in Molecular Biology). Located in the university area.

-          Centre de R&D IMPROVE, specialized in the extraction and purification of proteins of vegetable origin. Located outside the university area.

RegPep 2016
Posted the 2014/09/17
During the last RegPep meeting that took place in Kyoto, it was decided that the 2016 meeting would be organised in Rouen.
Peptide delivery for therapeutic and cosmetic applications
Posted the 2014/09/08
Organized by University of Rouen, Cosmetic Valley, CBS Technopole and GFPP, the Thematic Day: « Peptide delivery for therapeutic and cosmetic applications » will be held the November 26th 2014 at the Maison de l'Université, Campus Mont-Saint Aignan de l'Université de Rouen.

This meeting will bring together international experts including Ijeoma UCHEGBU (Nanomerics), Paolo BOTTI (Arisgen), Michel KHRESTCHATISKY (Vect-Horus), Joel RICHARD (Ipsen) and Karl LINTNER (KAL'Idées). Oral presentations will be selected from submitted abstracts.

Participation to this event is free but registration is mandatory.
More information here.

PeReNE at the 50th International Conference on Medicinal Chemistry (RICT 2014)
Posted the 2014/06/25
The PeReNE project will be present on a stand on the occasion of RICT 2014 (International Conference on Medicinal Chemistry). This conference will bring together approximately 600 industrial and academic researchers, experts of international level and high quality, around hot topics in R & D in the field of life sciences, with a particular focus on the molecular understanding of biological mechanisms, new approaches in chemo-therapeutic chemistry and biology, and therapeutic innovation. Peptides in therapy, in conjunction with the preoccupations of research projects underway in the area, is one of the themes chosen for this conference. For more information on the International Conference on Medicinal Chemistry, see the programme at
Lay-public conference 'La recherche des médicaments d'hier à aujourd'hui'
Posted the 2014/05/26
Related to RICT2014, Professor Jean Costentin will give a lay-public conference in the Chamber of the Région the July 2nd at 20h30. The title of the conference is : La recherche des médicaments d'hier à aujourd'hui 
Conference Michael Conlon
Posted the 2014/04/22
As part of the PeReNE project, Pr Michael Conlon, will present a conference entitled 'The multi-faceted therapeutic potential of host-defense peptides from frog skin', on May 6th at 11 am in the meeting room of PRIMACEN (3rd floor), at Rouen University on the campus of Mont-Saint-Aignan.
Posted the 2014/03/21

On March 25, Dr Yossan-Var TAN and Cattalina ABAD will give a seminar on 'PACAP and VIP receptors: A new therapeutic target for the treatment of multiple sclerosis'. The seminar will take place in room 308 (PRIMACEN meeting room) in the main building of the science faculty of Rouen.
seminar 'Neurosciences, Sciences cognitives, Neurologie, Psychiatrie'
Posted the 2014/03/13
During the seminar 'Neurosciences, Sciences cognitives, Neurologie, Psychiatrie', organized by the Faculty of Medicine and Health Sciences from the University de Brest, Jean-Claude Le Mével has given a talk intitled 'Les peptides du stress et leurs effets physiologiques'.


Open Doors Day of the University of Brest
Posted the 2014/02/17
During the Open Doors Day of the University of Brest, on 8 February 2014, more than 50 persons visit the Laboratory of Neurophysiology and attend some presentations on the cardiovascular effects of centrally administered neuropeptides.
2nd Belgian Peptide Group Meeting in Ghent, Belgium
Posted the 2014/01/22
The 2nd Belgian Peptide Group Meeting, organised under this auspices of the European Peptide Society, will take place at the culture and convention centre "Het Pand", in Ghent, Belgium, from 10th to 11th February 2014. This conference will feature four conferences by Helma Wennemers (ETH Zürich), Meritxell Teixidó (IRB, Barcelona), Paul Alewood (IMB, Brisbane) and Gilles Subra (IBMM, Montpellier) and will also have poster sessions. This meeting intends to cover various aspects of peptide research:synthesis, identification, pharmacology, drug discovery and development, delivery, peptide production,... etc. The deadline for abstract submission for poster presentation has been extended to January 31st. For more programme information, visit:
Conference by James Smith
Posted the 2014/01/17
Dr James Smith from University of Portsmouth will give a conference entitled ‘Atomic Force Microscopy at Portsmouth’. January 28th, 2014 at 13 h 30 in 308 room (PRIMACEN meeting room).


Conference by Dr Charles Pineau in Rouen
Posted the 2014/01/07
Dr Charles PINEAU (Director of the Proteomics platform Biogenouest) will give a lecture entitled "MALDI Imaging: applications, limitations and potential", in the PRIMACEN meeting room (room 308) on the 3rd floor of the Main Building of the Faculty of Technical and Sciences in Mont-Saint-Aignan, on February 18th, 2014 at 11 am.


Contract for engineer in proteomics
Posted the 2013/12/23
The PISSARO Platform is looking for an engineer in proteomics. It is a 1 year contract that can be completed by a second year on another contract. If interested in the position, please contact David Vaudry ( and Philippe CHAN (


PeReNE Newsletter: ISSN (International Standard Serial Number)
Posted the 2013/11/18
The Biobliothèque National de France has awarded an ISSN (International Standard Serial Number) to the letter of PERENE Project. An ISSN is a unique eight-digit number used to identify a print or electronic periodical publication. The ISSN facilitates IT management of publications (for subscription management, quotes, cataloging ...). The ISSN code for PeReNE is: ISSN 2270-1206
VASI Conference
Posted the 2013/11/18
Dr Fabio Apone, Arterra Bioscience srl, Napoly, Italy, will give a presentation entitled "Plant tissue cultures as source of cosmetic active ingredients". December, 9th 2013, 11h at Mont-Saint-Aignan.


Click to enlarge

Posted the 2013/11/14
Dr Asma Boussahel from University of Portsmouth will give a conference on novembre 14th, 2013, at 13 h 15entitled: ‘Peptide entrapment into polymer nanoparticles for delivery to the brain’.

PRIMACEN meeting room (308).

Connexions R&D
Posted the 2013/10/28
Dedicated to the exchanges between scientists from public and private institutions, the 4th edition of CONNEXIONS R&D will be held on Tuesday, December the 10th 2013 in Orléans (9h/17h).

More than 120 participants are expected to be at this scientific meeting, whose the aim is to meet the key players of the cosmetic research and to initiate innovative research projects.

In particular the program is a thematic workshop on "peptides and cosmetic applications", with the intervention of David Vaudry, for the University of Rouen and the PeReNE platform on:

              "The platform of peptide research, namely PeReNE, an opportunity for cosmetics."

Location: Turbulence-FRAC Centre in Orléans (9h/17h), 88 rue du Colombier (Rocheplatte Boulevard entrance), 45000 Orleans.

CONNECTIONS R&D is organized with the support of the State and the Centre Region.

Sign up:
Lecture / Course of Pr Jonathan Essex (Southampton)
Posted the 2013/10/24

Pr Jonathan Essex will give a lecture / course in Caen on the 29th october 2013.

UFR des Sciences Pharmaceutiques, Boulevard Becquerel, University of Caen Basse Normandie

Amphi 10

9H - 11H

Title :  Computer simulations of membrane systems

Joint TC2N and PeReNE conferences
Posted the 2013/10/16
Joint TC2N and PeReNE conferences at the Rouen University House (Mont-Saint-Aignan), 10h-12h, October, 24th.

Seminar of Charles Pineau
Posted the 2013/10/08
The seminar of Charles Pineau, originally scheduled on October 8, 2013, is postponed to a later date.
PeReNE will be present at the Science Festival in Rouen
Posted the 2013/09/24
The PeReNE project will have a booth during the Science Festival that will take place in Rouen from October 10 to 12. The PRIMACEN and PISSARO facilities will present their activities. Some visits of PRIMACEN will also be organised on October 8th.


Recruitment of Mr Paul Giuliani
Posted the 2013/09/24

Mr Paul Giuliani who did his Master training on the PeReNE project has now been recruited for a 21 month period to take care of the financial and administrative management of the project. Paul will also contribute to develop communication activities.
Seminar By Charles Pineau in Rouen
Posted the 2013/09/23
On October 8th, Dr Charles Pineau from Rennes, will come to Rouen University to give a seminar entitled 'MALDI Imaging: applications, limitations and potential'. The presentation will be at 11 AM in Rouen 308 (PRIMACEN) at the Sciences Faculty of Rouen University in Mont-Saint-Aignan.


VIP-PACAP and Related peptides 11 International Symposium
Posted the 2013/09/03

The 11th VIP-PACAP and Related peptides International Symposium took place in Pécs, Hungary from August 27 to 31, 2013. Over 160 people have contributed to this meeting where David Vaudry presented a poster of his work on PACAP in PC12 cells.

Visit of Pr Pietro Ghezzi
Posted the 2013/09/03
On September 2nd, Pr Pietro Ghezzi came to Rouen University to visit the PISSARO and PRIMACEN core facilities. He discussed with INSERM researchers of ongoing work and future collaboration. 
Researcher meeting in Rouen, 16th July 2013
Posted the 2013/08/30
Three researchers from Medway (Vladimir Gubala, Alison Edwards and Matthew Freddi) visited Rouen to undertake research discussions for project 3.8 “Targeting of chemotactic vasoactive peptide receptor signalings in neurovascular diseases”.

 Discussions involved a number of researchers from Rouen University (including Helene Castel, Isabelle Milazzo) as well as Caen (Ronan Bureau).

11th International Symposium on VIP, PACAP and Related Peptides
Posted the 2013/08/24

From August 27 to 31, 2013, the 11th International Symposium on VIP, PACAP and Related Peptides will take place in Pécs, Hungay ( Participants to the PeReNE project will present several posters and oral prosentations during this meeting. For more information regarding the program: To access the list of posters that will be presented:
Preparation of peptide-loaded nanoparticles by electrospraying
Posted the 2013/07/16
Drs. Manoochehr Rasekh, Marta Roldo and Eugen Barbu participated to a special training course organized by Profector Life Sciences on a Spraybase™ electrospray rig that is being used for the formulation of a range of peptide-loaded biocompatible nanocarriers aimed at drug delivery across challenging biological interfaces such as the blood-brain barrier.
Recruitment of Ms Julie Maucotel
Posted the 2013/07/15
Ms Julie Maucotel has been recruited by Rouen University to help researchers in their experiments on animal models. She will be in charge of some transgenic cell lines of animals deficient in some peptides and will contribute to the training of people on the PRIMACEN platform.
Seminar in Rouen by University of Kent researcher
Posted the 2013/07/15
Dr Matthew Freddi, from the University of Kent, will be giving a lecture entitled “Preparation of Urantide Loaded Nanoparticles” at the University of Rouen, on July 16th, 11am.

Postdoctoral position at the INRS-Institut Armand-Frappier centre in Quebec
Posted the 2013/07/11
The INRS-Institut Armand Frappier centre, University of Quebec, is offering a Postdoctoral position for someone with a good expertise in animal experiments and biochemistry. For more information about the position, please download the job description available here
Recruitment at the University of Caen Basse-Normandie
Posted the 2013/06/29
v style="zoom: 1;" dir="ltr">Ms Carla Jamous-Delepée will incorporate, as a post-doctoral researcher for 1 year, the CERMN team (University of Caen Basse Normandie) to develop molecular dynamics studies on neuropeptides, their analogues and the corresponding macromolecular complexes.</
Visit of Mr Richard Mutsa for 3 months a Rouen University
Posted the 2013/06/15
Mr Richard Mutsa, Student at the University of Portsmouth has joined INSERM Unit 982 (Rouen University) for a 3 month training with Dr Roger Cuby. Mr Mutsa will investigate the transduction pathways activated by the neuropeptide PACAP.
11th International Symposium on VIP, PACAP and Related Peptides
Posted the 2013/05/31

Please note that this is the last day to register to the PACAP/VIP meeting:


Support from GFPP meeting
Posted the 2013/05/28

The GFPP can support students who want to participate to international meetings or who would like to make a training in another laboratory. For more information, visit:
Next GFPP meeting in Normandy
Posted the 2013/05/28

The next GFPP (Groupe français des peptides et protéines) meeting will take place in Normandy in 2015 by Dr Jérome Leprince. web site:

GPCR signaling: a saga paved with nobel prizes
Posted the 2013/05/27
The GFPP meeting started by a conference of Professor Joël Bockaert entitled ‘GPCR signaling: a saga paved with nobel prizes’. Indeed, in 1971, Professor Earl Sutherland get the nobel price for the discovery of cAMP, then in 1994 Professor Alfred Gilman get the nobel price for the discovery and purification of G proteins, in 2000 Professors Paul Greengard, Eric Kandel and Arvird Carlsson get the nobel price for the reporting the role of GPCR in brain functions (and more precisely memory mechanisms). More recently, Richard Axel and Linda Buc get the nobel price in 2004 for the cloning of olfactory receptors. Last but not least was the nobel price awarded to Robert Lefkowitz and Brian Kobilka in 2012 for their work on GPCR structure. Some of the GPCR have peptides as ligands.
Position for a technician
Posted the 2013/05/27

A position for a technician in charge of real time PCR experiments and cell culture is now open at Rouen University. For more information, please contact Dr David Vaudry (


Job offer at INSERM Unit 982 (Rouen)
Posted the 2013/05/21
A position is now open at INSERM U982 for a technician in animal experimentation. The candidate will have to conduct surgery on rodents to help our researchers and students. The candidate will be in charge of several animal trangenic lines and will have to conduct genotyping. For more information, please contact Dr David Vaudry (
Funding obtained to support extended visit
Posted the 2013/05/16
April 2013

Dr Alison Edwards and Dr Vladimir Gubala at the Medway School of Pharmacy have been successful in securing further funds (£440) to facilitate researcher exchange with Dr Helene Castel at the University of Rouen for the project “Targeting of chemotactic vasoactive peptide receptor signalling in neurovascular diseases”.

The University of Kent offers an internal competition for additional research support where the main criteria are ‘excellence’ and the support of longer-term development of research in the Faculty of Science.

We plan that Dr Matthew Freddi will visit Helene’s team for a week in July 2013 to facilitate the transfer of knowledge between the Medway and Rouen research teams. This should enhance the design and application of the silica based nanoparticles (prepared at Medway) for the delivery of antagonists of the vasoactive neuropeptide urotensin II (UII) to tumours in the brain.

New Member of Staff at UoP
Posted the 2013/05/16
Dr Maryline Bossus joined the team on the 2nd April 2013 as postdoctoral researcher at the University of Portsmouth on a project entitled "Neuroendocrine disruption in Crustacea" under the workpackage "Central and peripheral peptidergic control of cardiovascular and ventilator activities and effects of endocrine disruptors". Formerly, Maryline studied fish physiology at the University of Montpellier. The current project will look into the effects of selective serotonin re-uptake inhibitors (SSRIs) on the bahaviour and gene expression in amphipod crustaceans.
Appointment of two researchers at Medway School of Pharmacy
Posted the 2013/05/03
Two researchers have begun working at the Medway School of Pharmacy in the UK on a new project entitled “Targeting of chemotactic vasoactive peptide receptor signalling in neurovascular diseases”. Dr Matthew Freddi and Mohammed Momin will work under Dr Alison Edwards and Dr Vladimir Gubala, in the Chemistry Drug Delivery group. The project is being conducted in collaboration with Dr Helene Castel at the University of Rouen and we look forward to further collaboration with other experts in the PeReNE network.

The goal of the current project is to develop a system for the targeted delivery of antagonists of the vasoactive neuropeptide urotensin II (UII) to tumours in the brain using silica-based nanocarriers. Dr Castel has shown that urotensin II, through activation of its receptor, favors pro-angiogenic cell recruitment and glioma cell invasion. Therefore the delivery of these antagonists provides a potential treatment to target this pathway. Work at Medway focuses on the preparation of silica based nanoparticles capable of systemic delivery of such antagonists.

Mohammed joined the Medway School of Pharmacy in 2005 and works as a Research Associate. Before this he worked for a number of academic institutions, biochemical and pharmaceutical companies. During this time he undertook an MSc in Analytical Chemistry of Clinical Materials at the Birkbeck College London. Mohammed obtained his BSc(Hons) in Applied Chemistry from the University of Kingston.

Matthew has been newly appointed as a Research Associate at the school, and comes directly from completing his PhD. Matthew graduated from The University of Nottingham in July 2012 where he was part of the EPSRC/AstraZeneca funded Doctoral Training Centre in Targeted Therapeutics within the School of Pharmacy. His PhD project investigated advanced drug delivery strategies for osteoarthritis, including both nanoparticle and hydrogel drug delivery systems. Matthew graduated from University of Nottingham with a BSc(Hons) in Biochemistry in 2007.

Promotion of the PeReNE project towards rge cosmetic industry
Posted the 2013/04/28
The rollup PERENE was presented on the Cosmetic Valley stand at In Cosmetics (International exhibition on materials and ingredients for the cosmetics industry), which was held in Paris from April 16 to 18,  2013. It will also be presented at trade fairs in Dubai and Shanghai in May.


New Researcher at Brest University (France)
Posted the 2013/04/22
Dr Gilmer Vanegas is working on the central and peripheral cardiovascular, ventilatory and locomotor  effects of various peptides including urotensin II (UII) and the urotensin II-related peptides (URPs).

Posted the 2013/04/08
Two postdoctoral scientists have been recruited at the University of Portsmouth to work on peptide-loaded nanocarriers designed for drug delivery across biological barriers.

Drs. Romaissa Boussahel and Manoochehr Rasekh have joined the research groups at the School of Pharmacy and Biomedical Sciences working towards the preparation and characterisation of polymeric nanoformulations aimed at drug delivery applications.

In close collaboration with researchers at Rouen, they will be using techniques such as nanoprecipitation and electrospraying to formulate a range of peptide-loaded biocompatible nanocarriers that will be further tested for their ability to efficiently deliver their cargo across challenging biological interfaces such as the blood-brain barrier.
Trainee for the management of the PeReNE project
Posted the 2013/04/03
Mr Paul Giuliani, student at Caen University in Master 2 ‘Expert in European projects for local development' has just started his final training at the University of Rouen, where he will participate in the financial and administrative management of the PeReNE project.
Arimura Foundation supports young investigators
Posted the 2013/04/02
Dear Colleagues,

 We are glad to announce that the Arimura Foundation supports young investigators to attend the meeting with travel awards. The award covers the registration fee so winners will receive free registration.

 Deadline for application for the travel award is April 30th, the deadline for early registration. Send application by email:

 Please note that the organizing committee cannot ensure that every applicant receives the award. If the number of applicants is higher than the number of possible awards, the  students who applied but receive no funding can still pay the early registration fee.


Please DO NOT pay the registration fee until a decision is made and you are notified (May 15th).



1. Short CV, with emphasis on works on VIP and PACAP field (not exceeding one page)

2. Abstract

3. Recommendation letter from supervisor

4. Certification of student status



 Dora Reglodi

Trainee for the management of the PeReNE project
Posted the 2013/03/11
On April 1st, Mr Paul Giuliani will join the management team of the PeReNE project at Rouen University. He will be involved in the completion of the first ERDF claim.
MMWS 2013 in Erlangen
Posted the 2013/03/08
Elke Haensele (University of Portsmouth) presented a poster entitled "Molecular Dynamics and Umbrella Sampling Simulations of 8-Arg-Vasopressin" at the Molecular Modeling Workshop in Erlangen, Germany.
1st SCT Workshop on Biologically Relevant Molecular Diversity - April 4th, 2013, Paris, France
Posted the 2013/02/27
1st SCT Workshop on Biologically Relevant Molecular Diversity 

April 4th, 2013 | Maison de la Chimie, Paris, France

Deadline for early bird fees is approaching!

Register before March 4 to benefit from the early bird fees.

Remark: Accommodation rates in Paris might raise quickly due to the Easter holidays. We advise you to book your accommodation early! Find out more on the accommodation page.


The French Society of Medicinal Chemistry (SCT) is pleased to announce the first edition of the SCT Workshop on “Biologically Relevant Molecular Diversity”, scheduled to be held on April 4th in Paris, France.

This one-day meeting is organised in addition to the 3 other SCT events, namely the annual “International Conference on Medicinal Chemistry” (RICT) (July 3-5, 2013, Nice), the “Young Researchers Days” (February 2013), and the autumn thematic one-day meeting, to better meet the needs of the SCT academic and industrial partners. 

The aim of this first SCT workshop is to provide medicinal chemists with state of the art methods and best practices in molecular diversity analysis of chemical libraries and compound collections. The workshop is meant to present and to discussmethods and strategies to analyse and optimise the molecular diversity of libraries covering library design, library comparison, and compound selection for the optimisation of compound collections in order to increase the probability of identifying high quality hits.

Confirmed Speakers

The speakers' short biographies and pictures are now available on the symposium website! Find out more on the internationally well-known speakers who will give presentations about diversity, with an emphasis on the molecular aspects involved in the interactions between molecules and biological targets.

Chemspace Session 
The Chemical Space Project 
Prof. Jean-Louis REYMOND (UNIVERSITY OF BERN, Switzerland) 
Feature-Based Pharmacophores for Molecular Profiling 
Navigation in Chemistry Space Towards Biological Activity 

Biospace Session 
Molecular Diversity: Why Do We Want it? What Do We Get? 
Merging Chemical and Biological Spaces 
Systematic Mapping of Target-Ligand Interactions Using Compound Activity Data 

Macrocycles Approaches for Protein-Protein Interactions 
Dr Daniel OBRECHT (POLYPHOR, Switzerland) 
Enriching Chemical Space by Diversity–Oriented Synthesis of Natural Product-like Compounds 

For further information and regular updates, please visit our website

Premier comité de pilotage du projet PeReNE
Posted the 2013/02/02
On Friday February 1st, 2013, the first PeReNE steering committee took place in Brighton.  The meeting organized by Paul Gard and his colleagues was devoted in the morning to the preparation of the first ERDF claim and the afternoon was an opportunity for presentations of some activities planned during the project. 
Documents provided during the meeting ‘Making a success of your project’
Posted the 2013/01/21
During the meeting ‘Making a success of your project’ of January 16th, 2013, a number of documents have been provided to the participants. Please find below some those documents which could help you.



Meeting ‘Making a success of your project’
Posted the 2013/01/17
On Wednesday January 16th, 2013, 4 members of the PeReNE project were present at the meeting ‘Making a success of your project’ organized at the Hotel de Region of Upper Normandy in Rouen. This meeting included an information session on the administrative and financial aspects of the project. The meeting also included a training on the presage software and an informal meeting with the Joint Technical Secretariat correspondent.
The PeReNE project in the Laboratory Magazine
Posted the 2013/01/17
An article on the project PERENE is published in the issue January 2013 of the "La Gazette du Laboratoire". You can find the full article here.
11th International Symposium on VIP, PACAP and Related Peptides
Posted the 2013/01/07

The 11th International Symposium on VIP, PACAP and Related Peptides will take place in Pecs, Hungary from August 27 to 31, 2013. For more information, please connect to: 
First Steering committee PERENE project- Brighton
Posted the 2013/01/07
The first PeReNE steering committe meeting will be held in Huxley Building on the Moulsecoomb campus of University of Brighton on february first.  Maps can be found at:
Understanding Bioavailability of Peptides
Posted the 2013/01/07
What sequence and structural factors influence the bioavailability of small peptides following ingestion? Which physiological parameters determine whether peptides reach and persist in the systemic circulation, and which models would be relevant to assess peptide bioavailability? The Seeker is looking for insightful submissions that are supported by peer-reviewed publications, in-silico modelling &/or existing research data. AWARD: $20,000 USD  |  DEADLINE: 1/09/13
Training within the project administration team of PeReNE
Posted the 2013/01/03
We are looking for an intern who will integrate our team at the University of Rouen for the administrative and financial management of the project PERENE. The person will have a key role in the success of the project so it will be very motivated and efficient. In interaction with partners, it will demonstrate autonomy while maintaining responsible manager constantly informed of the project. If the training goes well, it will be followed by a 2 year contract for the managemebnt of the Interreg PERENE project.
Research Associate position available
Posted the 2012/12/21
Myself and a colleague (Vlad Gubala) have a funded research associate position available for 12 months.

Project description:

“Targeting of chemotactic vasoactive peptide receptor signalling in neurovascular diseases”
The scope of the project is to synthesize novel hybrid silica-core-noble-metal shell based nanocarriers and investigate their capacity for the targeted delivery and controlled release of neuroactive peptides into malignant brain tumours. The nanocarriers will be evaluated by the collaborating research team at the University of Rouen, France to ascertain their efficiency of delivery in vitro and in vivo. Working closely with researchers at Rouen, the design of the nanocarriers is expected to be further optimised to enhance the delivery and the therapeutic effect.

Closing date: 13th Jan 2013
Interviews: 22/23/24th Jan 2013
We would like a start date of Feb/March 2013.

I have attached the full job description here as a PDF.

Applications are made online using the link below,224


Alison Edwards

GFPP congress, sète, may 26-31, 2013
Posted the 2012/12/12
The GFPP (Groupe Français des Peptides & Protéines) congress will take place at Sète, the may 26th to 31th, 2013. The registration fees are:

* Student+Post-Doc.: 330 Euros
* Academic: 470 Euros
* Industrial: 640 Euros

Important dates :
* Abstract submission (oral presentation) + Grants applications: 11 JANUARY
* Abstract submission (posters): 10 APRIL
* Registration: 10 APRIL

More information here :

Doctoral offer
Posted the 2012/11/28
As part of the PeReNE project, a doctoral offer is available at Laboratory of Ecotoxicology at the University of Le Havre, France. More information here.
Posted the 2012/11/26
The PeReNE project will be present at the 6th CBS meeting that will take place in Caen on Thursday, December 13th, 2012 to attend conferences on "Biomarkers: towards personalized medicine" and to present its activities in the field.
For more information, see
People exchange
Posted the 2012/11/26
Dr Alison Edwards and Dr Vladimir Gubala from Kent University will visiting Rouen University from December 10 to 12, 2012. 
Posted the 2012/11/18
The Chemistry Biology Health cluster is pleased to invite you to the 6th Norman Meeting on Chemistry Biology and Health onThursday, December 13th, 2012 in Caen.


The 2012 edition, entitled "Biomarkers: towards personalized medicine," is at the heart of a general reflection on the challenges of biomarkers and the way they open in the implementation of personalized medicine. The conferences will be structured around invited lectures and 3 poster sessions.

During this meeting, focused on neurological diseases (Alzheimer's in particular) and cancers, two main themes will be discussed: the first relates to biomedical imaging and in particular the development of radiotracers and contrast agents for imaging by positron emission tomography (PET) and magnetic resonance imaging (MRI) and their applications, and the second concerns the interest of the overall analysis of the metabolome, combined with that of the genome, transcriptome and proteome for biomarker identification used in the context of personalized medicine. The PERENE project is partner of this event.

All information about the program and registration forms are available on the website dedicated to the conference:
PeReNE Project
Posted the 2012/10/22
The European project Peptide Research Network of Excellence (PeReNE) was approved on October 11, 2012 by the Steering Committee of Interreg IVa France (Manche) - England Program. This project, at the initiative of the Researcher of the University of Rouen, aim to put Channel region at the forefront of the research on peptides based on 23 research teams and 3 facilities from INSERM, CNRS, University of Amiens, Rouen, Caen, Rennes, Brest, Exeter, Southampton, Portsmouth, Brighton, Sussex and Kent ( The Competitiveness Cluster CosmeticValley and two companies (BioSIMS et RootLines Technologies) are also partners in the project. The project will carry out 14 operations on collaborative research on bioactive peptides, with innovative industrial opportunities in the areas of biomediacal, cosmetic and agrifood. Planned actions also include scientific meetings, communication to the public, workshops, participation in international exhibitions and exchange with French and British companies.

To carry out these activities, the project benefits for the period 2012-2015 a European Grant of 2,79 millions of euros. Contact :

Conference announcements
Posted the 2012/10/11

Peptide: du principe actif aux applications thérapeutiques et cosmétiques

conf Several conferences will be held the november 14th 2012 at the Parc des Expositions of Rouen. More information here.
PhD studentship available
Posted the 2012/09/24
The details of the project and application process are available here. The closing date is the Sunday 28th October 2012.
Big Talents
Posted the 2012/07/01

On the occasion of the business convention Big Talents, a series of lectures on the potential of peptides in medicine and cosmetics will be given on November 14th, 2012.

Presentation of the PeReNE project
Posted the 2012/06/28

The PeReNE project has been presented a the scientific board of the Cosmetic Valley on June 21.

BPS Focused Meeting on Neuropeptides
Posted the 2012/03/12

BPS Focused Meeting on Neuropeptides - Abstract submission is now open, the closing deadline for submissions is 15 April

    Date: 07 june 2012 - 09 june 2012
    Location: King's College London
    Event Summary

CPD approval applied for

This 2.5 day course brings together neuropeptide and TRP nerve activation interests from the UK, Europe and America. There is a list of speakers who are carrying out cutting edge translational studies. In addition, there will be talks chosen from the submitted abstracts as well as poster sessions. This meeting will offer bursaries for young scientists and networking opportunities for all. We are arranging a social programme to fit with our location, right at the centre of London. This BPS meeting is combined with the 9th Joint meeting or the European Neuropeptide Club and the American Summer Neuropeptide Conference.

For registration, please check the following adress:
Neuropeptides 2012 230212.pdf

Posted the 2012/02/02
Dr Hubert Vaudry will give a lecture 'Of Frogs and Men: the singular contribution of amphibians to the discovery of mammalian neuropeptides' on Sunday 12th of February, 2012 at the United Arab emirates University (UAEU).
SFEAP 2012
Posted the 2012/02/01
On behalf of the French Proteomic & Electrophoresis Society (SFEAP), the municipality of Rouen, the University of Rouen and the Regional Council of Haute-Normandie, we would like to invite you to Rouen to participate in the 29th Congress of our society, which will be held on 15-17 October, 2012. The venue of the congress will be the "Halle aux Toiles", a historical building located in downtown Rouen, near the bank of the Seine River, within walking distance from the Place du Vieux-Marché (where Joan of Arc was burnt alive in 1431) and the famous Cathedral, painted by Claude Monet.
The scientific program will encompass all facets of state-of-the-art Proteomics in both the basic and clinical arenas. All the fields of Human Health Proteomics, Plant Proteomics and Microbial Proteomics will be covered all along the invited lectures, oral communications and poster sessions. The social events, included in the registration fee, will comprise a gala dinner in the city, near the river and a visit of Rouen downtown to discover all the architectural treasures of the city.
We very much hope that you will be able to join us for this major proteomic forum in Rouen in 2012. You will be able to learn about the most recent advances in proteomics and related disciplines, to meet old friends and colleagues, and to initiate new relationships. In the meantime, if there is anything that we can do to help you attend the Congress, please do not hesitate to contact us directly at

For more information please visit the web site of the meeting :

   With best wishes

Pascal CosetteOdile Schiltz
Chairman of the local organizing committee   President, SFEAP
32nd European Peptide Symposium
Posted the 2012/01/30
The 32nd European Peptide Symposium (EPS) will be held from 2-7 September 2012, at Megaron, Athens, Greece. For more information, connect to the 32EPS web site:
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